butabarbital boosts toxicity of methoxyflurane by growing metabolism. Contraindicated. Greater metabolism of methoxyflurane to nephrotoxic compounds.
butabarbital will minimize the extent or effect of aprepitant by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of.
butabarbital will minimize the extent or impact of alprazolam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.
Other Unwanted effects not outlined might also come about in certain patients. When you recognize another consequences, Examine together with your healthcare Expert.
benzhydrocodone/acetaminophen and butabarbital each improve sedation. Avoid or Use Alternate Drug. Restrict use to people for whom alternative treatment method solutions are insufficient
butabarbital and daridorexant both enhance sedation. Modify Therapy/Keep track of Intently. Coadministration improves chance of CNS depression, which can lead to additive impairment of psychomotor general performance and lead to daytime impairment.
Appropriate reports thus far have not shown pediatric-distinct difficulties that would Restrict the usefulness of butabarbital in youngsters when made use of right before a surgical technique. On the other hand, security and efficacy have not been recognized in little ones to take care of sleeplessness. Geriatric
butabarbital will minimize the level or outcome of lefamulin by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Stay away from or Use Alternate Drug. Prevent coadministration of lefamulin with potent or moderate CYP3A inducers unless the reward outweighs challenges. Observe for minimized efficacy.
The existence of other health-related troubles may perhaps influence the usage of this medication. Be sure you inform your health practitioner For those who have another clinical challenges, Primarily:
butabarbital will lessen the extent or influence of buprenorphine subdermal implant by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Check Closely. Keep track of people previously on buprenorphine subdermal implant who call for newly-initiated treatment with CYP3A4 inducer more info for indications and indicators of withdrawal.
butabarbital will reduce the extent or influence of montelukast by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Importance Not known.
Regardless that butabarbital is taken at bedtime, it could result in many people to feel drowsy or fewer inform on arising. Don't push or do anything else which could be unsafe till you know the way this medicine influences you.
Its intermediate duration of action provides butabarbital an abuse probable a little bit lower than secobarbital. Butabarbital can be hydrolyzed to valnoctamide.[four] Stereoisomeres of butabarbital
butabarbital will enhance the degree or influence of clopidogrel by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.